Understanding and exploiting molecular machines for chemistry, biology, and medicine
A chemical and synthetic biology group at UC Berkeley

Our Research

Repurposing the ribosome to synthesize novel natural products, stabilized proteins, and new materials
Repurposing the ribosome to synthesize novel natural products, stabilized proteins, and new materials
Delivering therapeutic proteins to the cytosol and nucleus - for real
Delivering therapeutic proteins to the cytosol and nucleus - for real
Understanding and exploiting information transfer across cellular membranes
Understanding and exploiting information transfer across cellular membranes
Visualizing organelles at super-resolution for almost forever and in multiple colors
Visualizing organelles at super-resolution for almost forever and in multiple colors

Latest News

March 27, 2025
Schepartz Lab in the spotlight as American Peptide Society’s Lab of the Month!
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February 27, 2025
C-GEM advance highlighted by the American Peptide Society and Chemical & Engineering News
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August 14, 2024
Join us in congratulating the 2024 C-GEM Summer Undergraduate Research Program (SURP) Scholars!! They all completed and presented projects with mentorship from the Schepartz, Francis, and Cate Lab!
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March 5, 2024
New paper:  HOPS-Dependent Endosomal Escape Demands Protein Unfolding to be published in ACS Central Science. Congrats to Maddie Zoltek, Angel Vázquez, Xizi Zhang, Neville Dadina, and Lauren Lesiak!!!
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